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为什么说Ⅱ型糖尿病患者应广泛使用他汀类药物？

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2018-08-06

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       美国内科医师会建议，Ⅱ型糖尿病应广泛使用他汀类降脂药以预防心血管病的发生。要认识到控制心血管病高危因素（特别是高血压与胆固醇浓度）与控制血糖浓度同样重要。糖尿病的不良预后是微血管或大血管病的并发症，前者有视网膜病和肾病，后者有冠状动脉病、外周血管和脑血管病。一些研究证实80%糖尿病患者将死于大血管病，因此，学会提出以下建议：（1）所有确诊为冠状动脉疾病和Ⅱ型糖尿病的成人患者应接受他汀类药物作为心血管病的二级预防；（2）所有Ⅱ型糖尿病与其他心血管病高危因素（包括高血压、吸烟、左心室肥厚和年龄大于55岁）患者应接受他汀作为大血管病的一级预防；（3）已接受他汀类的患者至少应服中等剂量，即阿伐他汀20㎎，一天一次，洛伐他汀40㎎，一天一次，普伐他汀均

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